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The Benefits of Acupuncture for the Immune System

Written by Dr. med. Francesco Giombini | 27 Sep 2024

Acupuncture not only relieves chronic pain and anxiety, but recent studies confirm that it boosts the immune system! Let's explore how acupuncture can become an ally in strengthening our natural defences, improving the body’s ability to fight infections and diseases.

Acupuncture and the Immune System: A Scientific  Connection

The immune system is the body’s natural defence against infections and diseases. It is composed of a complex network of cells, tissues, and organs that work together to protect the body. Immune cells, such as white blood cells, are responsible for detecting and destroying pathogens like bacteria, viruses, and cancer cells.

Several studies have shown that acupuncture can modulate the activity of immune cells. For example, research has demonstrated increased production of Natural Killer (NK) cells, a type of white blood cell that plays a crucial role in identifying and destroying cells infected by viruses or transformed into cancer cells. Additionally, acupuncture seems to stimulate the production of cytokines, proteins that regulate the intensity and duration of immune responses.

This stimulation of the immune system does not occur randomly. In fact, acupuncture has a regulatory effect, balancing the immune response and preventing overreactions, which could damage healthy tissues. This is particularly relevant in autoimmune diseases, where the immune system mistakenly attacks the body’s own cells.

Clinical Studies and Promising Results

The scientific validity of acupuncture in strengthening the immune system is supported by numerous clinical studies. The results to date are promising and demonstrate  that acupuncture could be used as part of an integrated approach to improve immune health.

Effects:

  • Reduction in serum IgE levels:
    Acupuncture significantly reduced serum IgE levels in patients with allergic rhinitis, which led to a decrease in allergic symptoms such as nasal congestion, itching, and sneezing. (Feng et al., 2015)
  • Improved respiratory function:
    Acupuncture has been shown to improve respiratory function in patients with allergic rhinitis, reducing congestion and enhancing respiratory capacity (Roberts et al., 2008).
  • Improved quality of life:
    Acupuncture improved the quality of life for patients with allergic rhinitis. (Feng et al., 2015)
  • Anti-inflammatory effects:
    Acupuncture, particularly at point ST36, has shown anti-inflammatory effects in animal studies through mechanisms such as vagus nerve activation and modulation of molecular pathways (Oh & Kim, 2022).
  • Reduction of chronic low-grade inflammation:

    Acupuncture has been associated with a reduction in chronic low-grade inflammation. Recent studies suggest acupuncture can modulate pro-inflammatory cytokines and promote immune balance, reducing chronic inflammation (Zhang et al., 2023).

  • Increased levels of white blood cells (WBCs) and neutrophils:
    Acupuncture significantly increased white blood cell and neutrophil levels in patients with chemotherapy-induced leukopenia (Shih et al., 2021). Acupuncture also boosted NK cell activity and interleukin-2 (IL-2) levels in the peripheral blood of cancer patients, suggesting improved immune function (Wu et al., 1994).
  • Improvement in immunosuppressive status in patients with sepsis:
    Acupuncture has been shown to improve immunosuppressive status and modulate systemic inflammation in patients with sepsis, while also protecting against organ damage (Yang et al., 2023).
  • Improved quality of life for patients with autoimmune diseases:
    Studies by Shang et al. (2020), Zan-Bar et al. (2004), and Dang et al. (2021) demonstrate that acupuncture effectively improves symptoms of autoimmune diseases such as rheumatoid arthritis and ankylosing spondylitis. Significant improvements in pain reduction, quality of life, and immune markers were observed in these patients.

Acupuncture as Support in Cancer Therapies

Another area where acupuncture is showing potential is in supporting cancer patients. Cancer and its treatments, such as chemotherapy and radiation, can significantly weaken the immune system, leaving patients vulnerable to infections and other complications.

Acupuncture can help mitigate some of the side effects of these treatments, such as nausea, fatigue, and pain. Some studies confirm that acupuncture may also improve immune function in cancer patients by increasing white blood cell production and enhancing the body’s ability to fight infections. These findings indicate that acupuncture could be a valuable adjunct to conventional therapies, helping to maintain a more robust immune system during critical phases of treatment.

Acupuncture as a Preventive Method

Not only can acupuncture be helpful in treating diseases, but it could also play a significant role in prevention. A strong immune system is crucial to preventing a wide range of diseases, from common infections like colds to more serious illnesses such as influenza and even certain forms of cancer.

Regular acupuncture sessions may serve as an effective preventive strategy, especially for individuals more vulnerable to infection, such as the elderly, people with chronic illnesses, or those under chronic stress. Acupuncture may help maintain an optimal balance in the immune system, preventing a decline in defenses and improving the body’s ability to respond to external threats.

In this context, acupuncture should not be viewed as a cure-all, but rather as an important element in an overall wellness strategy, which includes a balanced diet, regular exercise, and a healthy lifestyle.

Possible Mechanisms of Action

To better understand how acupuncture affects the immune system, it is useful to consider the possible mechanisms of action proposed by scientific research. One of the main mechanisms is the modulation of the central and peripheral nervous systems. Acupuncture stimulates skin nerves, which send signals to the brain and spinal cord, triggering a cascade of neurochemical responses.

These responses include the release of endorphins and other neurotransmitters, which not only relieve pain but also impact the immune system. For example, acupuncture has been shown to reduce levels of cortisol, a stress hormone that, when elevated chronically, can suppress immune function. By reducing stress, acupuncture may help maintain a more active and responsive immune system.

Another proposed mechanism involves acupuncture's effect on inflammation. While inflammation is an essential immune response, chronic inflammation can damage tissues and weaken the immune system. Acupuncture has been shown in some studies to reduce inflammatory markers in the blood, suggesting it may help prevent or reduce chronic inflammation.

Conclusion

In summary, acupuncture appears to have significant potential benefits for the immune system. While it does not replace conventional medical treatments, it can be effectively integrated into a comprehensive therapeutic approach, enhancing the body’s ability to fight infections and diseases. Given its ability to modulate immune responses, reduce stress, and alleviate inflammation, acupuncture is a valuable resource for those seeking to strengthen their natural defences.

 

 

Bibliography:

  • Yin, Zihan, Jun Zhou, Manze Xia, Zhenghong Chen, Yaqin Li, Xinyue Zhang, Xiang Li, et al. "Acupuncture on mild cognitive impairment: A systematic review of neuroimaging studies." Frontiers in Aging Neuroscience 15 (February 15, 2023);
  • Liu, Jiao, Chunyan Li, Hongwei Peng, Kunqiang Yu, Jing Tao, Ruhui Lin, and Lidian Chen. "Electroacupuncture attenuates learning and memory impairment via activation of α7nAChR-mediated anti-inflammatory activity in focal cerebral ischemia/reperfusion injured rats." Experimental and Therapeutic Medicine 14, no. 2 (August 2017): 939–46.
  • Zheng, Cai-Xia, Min Lu, Ya-Bi Guo, Feng-Xia Zhang, Hua Liu, Feng Guo, Xiao-Lin Huang, and Xiao-Hua Han. "Electroacupuncture Ameliorates Learning and Memory and Improves Synaptic Plasticity via Activation of the PKA/CREB Signaling Pathway in Cerebral Hypoperfusion." Evidence-based Complementary and Alternative Medicine: eCAM 2016 (2016);
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  • Cl, Hsieh, Lin Jg, Li Tc, and Chang Qy. "Changes of Pulse Rate and Skin Temperature Evoked by Electroacupuncture Stimulation with Different Frequency on Both Zusanli Acupoints in Humans." PubMed. Accessed July 11, 2024.
  • H, Kim, Park Hj, Han Sm, Hahm Dh, Lee Hj, Kim Ks, and Shim I. "The Effects of Acupuncture Stimulation at PC6 (Neiguan) on Chronic Mild Stress-Induced Biochemical and Behavioral Responses." PubMed, 2009.
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